Role of Clinical Trials in Diabetes Research
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High cholesterol itself doesn’t usually cause symptoms, which is why it’s often called a “silent” condition. Many people don’t realize they have it until it leads to serious complications like a heart attack or stroke. However, some indirect signs and related conditions may indicate high cholesterol:
Chest Pain (Angina) – Caused by reduced blood flow due to plaque buildup in arteries.
Xanthomas – Yellowish deposits of cholesterol under the skin, often around the eyes, elbows, knees, or hands.
Corneal Arcus – A grayish or white ring around the cornea, more common in older adults but can be a sign of high cholesterol in younger people.
Shortness of Breath & Fatigue – If cholesterol buildup leads to heart disease, it can reduce oxygen supply.
Erectile Dysfunction – Poor blood flow caused by clogged arteries may contribute to ED.
High Blood Pressure – Cholesterol buildup can make arteries stiffer, leading to increased blood pressure.
Serious Complications (That May Be the First Sign):
Stroke – Caused by restricted blood flow to the brain.
Heart Attack – Due to blocked coronary arteries.
Peripheral Artery Disease (PAD) – Pain or numbness in the legs due to clogged arteries.
How to Know for Sure? A blood test (lipid panel) is the only way to confirm high cholesterol. It measures:
Total cholesterol
LDL (“bad” cholesterol)
HDL (“good” cholesterol)
Triglycerides
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High blood pressure (hypertension) is often called the “silent killer” because it usually has no obvious symptoms until it reaches dangerous levels. However, some people with very high blood pressure may experience warning signs.
Possible Signs & Symptoms of High Blood Pressure:
Frequent Headaches – Especially in the morning or at the back of the head.
Dizziness or Lightheadedness – Can be a sign of dangerously high BP.
Blurred Vision or Vision Changes – High BP can damage blood vessels in the eyes.
Chest Pain – Could indicate heart strain or an impending emergency.
Shortness of Breath – If the heart is struggling to pump blood effectively.
Nosebleeds – Occasional, unexplained nosebleeds can be linked to high BP.
Fatigue or Confusion – Poor circulation to the brain may cause these symptoms.
Pounding Sensation in the Chest, Neck, or Ears – Especially noticeable when stressed or exerting yourself.
Severe Hypertension (Hypertensive Crisis) – Emergency Signs:
Seek immediate medical attention if you experience:
Severe headache Severe chest pain
Difficulty breathing
Sudden vision loss
Severe anxiety or confusion Nausea or vomiting
How to Know for Sure?
A blood pressure check is the only way to confirm high BP. Readings are measured in mmHg:
Normal: Below 120/80 mmHg
Elevated: 120-129 / <80 mmHg
Hypertension (Stage 1): 130-139 / 80-89 mmHg
Hypertension (Stage 2): 140+/90+ mmHg
Hypertensive Crisis: 180+/120+ mmHg (Seek emergency care)
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Truth About Diabetes
Diabetes is a chronic condition that affects how your body processes blood sugar (glucose). There are two main types: Type 1 diabetes (autoimmune, usually starts in childhood) and Type 2 diabetes (lifestyle-related, more common in adults).
Common Symptoms of Diabetes (Both Types)
Frequent Urination (Polyuria) – Excess sugar in the blood causes the kidneys to work harder, leading to increased urination.
Excessive Thirst (Polydipsia) – Due to frequent urination and dehydration.
Extreme Hunger (Polyphagia) – Despite eating, the body doesn’t use glucose properly, causing increased appetite.
Unexplained Weight Loss – More common in Type 1 diabetes; the body burns fat and muscle for energy.
Fatigue – Due to the body’s inability to use glucose efficiently.
Blurred Vision – High blood sugar affects fluid levels in the eyes.
Slow-Healing Wounds & Infections – High blood sugar weakens the immune system and damages blood vessels.
Tingling, Numbness, or Pain in Hands & Feet – A sign of diabetic neuropathy (nerve damage).
Dark Skin Patches (Acanthosis Nigricans) – Dark, velvety patches on the neck, armpits, or groin, often a sign of insulin resistance (common in Type 2 diabetes).
